<p>The role of the sensorimotor component in verbal information processing is currently widely discussed. We hypothesize that the type of motor response may influence behavioral and electrophysiological measures in an orthographic (spelling) decision task. Event-related potentials (ERP) were recorded in 42 right-handed participants during an orthographic decision task. Half the participants were instructed to press with the right hand on correctly spelled words and the left hand on misspelled words, while the other half were instructed to do the opposite. Motor responses to correctly spelled words were shorter for the dominant hand than the non-dominant hand, which may be due to the overlap of semantic and motor representations (the stimulus-response compatibility effect). In addition, reaction times to misspelled words were longer than those to correctly spelled words only in the group of participants responding with the dominant hand to correctly spelled words. The P200 and N400 ERP components did not depend on the type of motor response. However, in the group of participants who pressed correctly spelled words with the right hand, the amplitude of the P600 component was greater for misspelled words than for correctly spelled words. Thus, the type of motor response influenced the effects associated with recognizing the correctness of the spelling of words.</p>