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<p>Tetracyclines (TCs) have been widely utilized in the livestock industry in recent years due to their advantages, including a broad antibacterial spectrum, low cost, and various administration methods. However, the misuse of TCs has become increasingly concerning. Therefore, achieving accurate and rapid detection of TCs residues is of significant importance. Fluorescent sensors have found extensive application in drug residue detection owing to their high sensitivity, selectivity, rapid response time, and capabilities for real-time monitoring. By synthesizing relevant research findings from recent years, this article elucidates the operational mechanisms of fluorescent sensors, systematically analyzes the research achievements related to fluorescent sensors such as carbon quantum dots, metal nanoclusters, and metal–organic frameworks in detecting TCs residues in food, and forecasts their developmental prospects. The aim is to promote further innovation and advancement in drug residue detection technology, thereby ensuring food safety.</p>

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Research progress on detecting tetracycline antibiotic residues in food using fluorescence sensors

  • 期刊论文

  • 发表日期：

    2026年3月3日

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  • Ying Wang,
  • Hua Wang,
  • Lei Zhu,
  • Jinneng Wang,
  • Zeyan Xie,
  • Haifeng Yang,
  • Yukou Du

摘要

Tetracyclines (TCs) have been widely utilized in the livestock industry in recent years due to their advantages, including a broad antibacterial spectrum, low cost, and various administration methods. However, the misuse of TCs has become increasingly concerning. Therefore, achieving accurate and rapid detection of TCs residues is of significant importance. Fluorescent sensors have found extensive application in drug residue detection owing to their high sensitivity, selectivity, rapid response time, and capabilities for real-time monitoring. By synthesizing relevant research findings from recent years, this article elucidates the operational mechanisms of fluorescent sensors, systematically analyzes the research achievements related to fluorescent sensors such as carbon quantum dots, metal nanoclusters, and metal–organic frameworks in detecting TCs residues in food, and forecasts their developmental prospects. The aim is to promote further innovation and advancement in drug residue detection technology, thereby ensuring food safety.