Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

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2024年1月17日

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Mickey Konings,
Bert Gerrits van den Ende,
Mirthe W. J. Raats,
Ahmed Hassan Fahal,
Wendy W. J. van de Sande,
Ferry Hagen

摘要

Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.