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<p>Phagocytosis is a fundamental biological process in the immune system whereby phagocytic cells eliminate pathogens and apoptotic cells. This mechanism plays a central role in ensuring the effectiveness of innate immunity and in activating the antigen recognition and response processes of acquired immunity. This review discusses the importance of phagocytosis in the immune system, its molecular mechanisms, associated disorders, relationship with immunodeficiencies, and its role in vaccine design. In this context, a deeper understanding of phagocytosis may contribute both to improved approaches for the treatment of immunodeficiencies and to the development of next-generation vaccines and immunotherapies.</p>

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The importance of phagocytosis and its effect on the immune system

  • 期刊论文

  • 发表日期：

    2026年5月8日

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  • Hamra Sude Gençoğlu,
  • Esra Aydemir,
  • Furkan Ayaz

摘要

Phagocytosis is a fundamental biological process in the immune system whereby phagocytic cells eliminate pathogens and apoptotic cells. This mechanism plays a central role in ensuring the effectiveness of innate immunity and in activating the antigen recognition and response processes of acquired immunity. This review discusses the importance of phagocytosis in the immune system, its molecular mechanisms, associated disorders, relationship with immunodeficiencies, and its role in vaccine design. In this context, a deeper understanding of phagocytosis may contribute both to improved approaches for the treatment of immunodeficiencies and to the development of next-generation vaccines and immunotherapies.