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<p>The MYC family has been the subject of extensive research in the field of cancer, yet the mechanisms by which these factors operate in the context of endometriosis remain unclear. Considering the existing studies on the MYC family and diseases of the female reproductive system, this review examines the role of MYC family members in regulating cell proliferation and metabolic activity in endometriosis. Furthermore, the study explores the potential association between the MYC family and endometriosis, drawing parallels with its established role in cancer and findings from other gynecological diseases. The primary areas of discussion include cell proliferation and invasion, hormone dependence, and epigenetic regulation. The review also considers inhibitors of the MYC family and other related molecules that may affect MYC expression. The findings of this study suggest significant potential for the MYC family to play a pivotal role in the context of endometriosis. It is anticipated that advancements in technology will stimulate further research in this area and facilitate the development of clinically applicable therapeutic strategies.</p>

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MYC: unveiling novel therapeutic avenues for endometriosis

  • 期刊论文

  • 发表日期：

    2026年3月25日

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  • Xiaofang Ge,
  • Chenjing Yue,
  • Maoxiang Zhang,
  • Mengze Wang,
  • Jiayu Liu,
  • Aifang Jiang,
  • Zhenhai Yu

摘要

The MYC family has been the subject of extensive research in the field of cancer, yet the mechanisms by which these factors operate in the context of endometriosis remain unclear. Considering the existing studies on the MYC family and diseases of the female reproductive system, this review examines the role of MYC family members in regulating cell proliferation and metabolic activity in endometriosis. Furthermore, the study explores the potential association between the MYC family and endometriosis, drawing parallels with its established role in cancer and findings from other gynecological diseases. The primary areas of discussion include cell proliferation and invasion, hormone dependence, and epigenetic regulation. The review also considers inhibitors of the MYC family and other related molecules that may affect MYC expression. The findings of this study suggest significant potential for the MYC family to play a pivotal role in the context of endometriosis. It is anticipated that advancements in technology will stimulate further research in this area and facilitate the development of clinically applicable therapeutic strategies.