Objective <p>To explore the combined effects of COVID-19 and the infant formula shortage.</p> Methods <p>A cross-sectional survey explored breastfeeding behavior by COVID-19 infant feeding guidance, access to lactation support, and awareness and effect of the infant formula shortage. A multilinear regression model with backward elimination with bootstrapping was used to determine statistically significant predictors of breastfeeding duration. Text responses were analyzed to calculate the number and type of effects of the infant formula shortage.</p> Results <p>The number of effects of the infant formula shortage on the family, access to lactation support in the hospital, and number of hours of employment outside the home were the three most predictive variables for breastfeeding duration. However, access to lactation support was the only predictor that was statistically significant. Free form text responses demonstrated that formula feeding and some breastfeeding parents felt stress from the infant formula shortage.</p> Discussion <p>Access to lactation support in the hospital is widely recognized as a predictor of breastfeeding success. The decrease in lactation support that occurred during the COVID-19 pandemic may have created a barrier to breastfeeding. It is also remarkable that, regardless of feeding practice, the infant formula shortage created stress for families.</p> Conclusions for Practice <p>Access to a lactation consultant continues to be a significant contributor to breastfeeding behavior. Infant formula shortages may create risks for formula fed and breastfed infants. Breastfeeding protection and promotion may be a critical step in decreasing dependence on infant formula.</p>