Birth Outcomes Among People with Hepatitis C in Pregnancy — Three U.S. States, 2018–2021

期刊论文
发表日期：

2024年2月28日

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Kate R. Woodworth,
Suzanne M. Newton,
Ayzsa Tannis,
Megan R. Reynolds,
Emily O. Olsen,
Lindsey Sizemore,
Heather Wingate,
Lauren Orkis,
Bethany Reynolds,
Nicole Longcore,
Nadia Thomas,
Shin Y. Kim,
Lakshmi Panagiotakopoulos,
Carolyn Wester,
Dana Meaney Delman,
Suzanne M. Gilboa,
Van T. Tong

摘要

Introduction

There are limited and conflicting data regarding the impact of hepatitis C in pregnancy on adverse birth outcomes.

Methods

Using the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET), a large surveillance cohort, we describe birth outcomes among a cohort of people with HCV in pregnancy in total and by reported substance use.

Results

Among 1418 infants, 89% were born to people with reported substance use during pregnancy. The proportion born preterm was 20%, 13% were small-for-gestational age and 34% of term infants required intensive care.

Conclusions

Assessments of recent changes to recommendations for HCV screening in pregnancy should evaluate the impact on maternal access to care for both HCV treatment as well as comorbidities such as substance use disorder which may contribute to adverse birth outcomes.