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Objective <p>This study evaluated the potential of bioactive peptides (BaPs) and microencapsulated butyric acid (EBA) as a substitute for antibiotic enramycin in broiler chickens.</p> Methodology <p>A total of 600 broiler chicks (Ross-308) were divided into 5 treatments, having 6 replicates of 20 birds each under a completely randomized design. The treatments were: (1) Control (C) basal diet, (2) basal diet + 200&#xa0;g/ton enramycin (A), (3) basal diet + 300&#xa0;g/ton EBA, (4) basal diet + BaPs at 200&#xa0;g/ton (BaP2), and (5) basal diet + BaPs at 300&#xa0;g/ton (BaP3).</p> Results <p>The results indicated that during the finisher (22-35d) and overall period (1-35d), weight gain, feed conversion ratio, and production number were significantly improved (<i>P</i> ≤ 0.05) in all the supplemented groups as compared to the control. Similarly, the carcass traits (carcass weight, leg quarter, and breast weight), and immunity were also enhanced (<i>P</i> ≤ 0.05) in all the additive groups than in the control, especially in the BaP2 group. The intestinal morphometrics were considerably (<i>P</i> ≤ 0.05) improved in the EBA among the additive groups as compared to the control. Moreover, notably (<i>P</i> ≤ 0.05) reduced counts of pathogenic bacteria and increased levels of <i>Lactobacilli</i> were found in all the additive groups as compared to the control. The digestibility of CP was significantly higher (<i>P</i> ≤ 0.05) in BaP3 as compared to the control.</p> Conclusions <p>Supplementing broiler diets with EBA and BaPs effectively improved growth performance, gut health, and nutrient utilization, offering a viable solution for antibiotic-free broiler production.</p>

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Effect of Bioactive Peptides and Encapsulated Butyric Acid on Growth Performance, Gut Health, Immune Status and Nutrient Digestibility in Broiler Chickens

  • 期刊论文

  • 发表日期：

    2025年9月12日

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  • Mohammad Ahmad Qazi,
  • Ehsaan Ullah Khan,
  • Saima Naveed,
  • Shahid Mehmood,
  • Muhammad Muneeb,
  • Muhammad Talha,
  • Muhammad Shabir Shaheen,
  • Sohail Ahmad

摘要

Objective

This study evaluated the potential of bioactive peptides (BaPs) and microencapsulated butyric acid (EBA) as a substitute for antibiotic enramycin in broiler chickens.

Methodology

A total of 600 broiler chicks (Ross-308) were divided into 5 treatments, having 6 replicates of 20 birds each under a completely randomized design. The treatments were: (1) Control (C) basal diet, (2) basal diet + 200 g/ton enramycin (A), (3) basal diet + 300 g/ton EBA, (4) basal diet + BaPs at 200 g/ton (BaP2), and (5) basal diet + BaPs at 300 g/ton (BaP3).

Results

The results indicated that during the finisher (22-35d) and overall period (1-35d), weight gain, feed conversion ratio, and production number were significantly improved (P ≤ 0.05) in all the supplemented groups as compared to the control. Similarly, the carcass traits (carcass weight, leg quarter, and breast weight), and immunity were also enhanced (P ≤ 0.05) in all the additive groups than in the control, especially in the BaP2 group. The intestinal morphometrics were considerably (P ≤ 0.05) improved in the EBA among the additive groups as compared to the control. Moreover, notably (P ≤ 0.05) reduced counts of pathogenic bacteria and increased levels of Lactobacilli were found in all the additive groups as compared to the control. The digestibility of CP was significantly higher (P ≤ 0.05) in BaP3 as compared to the control.

Conclusions

Supplementing broiler diets with EBA and BaPs effectively improved growth performance, gut health, and nutrient utilization, offering a viable solution for antibiotic-free broiler production.