<p>This novel exploration investigates an implication of slippery magnetized suction/injection nanofluid flow, focusing on heat and mass transfer across a Rampant Cone with volumetric heat source. By applying similarity transformation, the governed flow equations are transmuted into a dimensionless ODE’s form and then handled numerically using the Keller-box approach. When dealing with boundary-layer problems, the Keller-box approach maintains its accuracy and robustness. Nonetheless, its efficiency diminishes and it may encounter convergence challenges in highly nonlinear systems, intricate geometries, or dynamic boundaries. Tables and figures present the detailed analysis of the influence of different controlling &#xa0;parameters on the flow characteristics. The findings show that the velocity, temperature, and concentration diminish over suction. When the thermophoresis parameter increases, the concentration and temperature also increase. The effect of heat sink (B) is a reduction in the temperature of the boundary layer and an increase in the concentration profile at the same time. In contrast, a heat source raises temperature and reduces concentration. Increasing magnetic parameter (M) and suction (f_w) reduce the coefficient of skin-friction. The numerical results exhibit strong agreement with previously published studies, reinforcing the accuracy and reliability of the findings. Nanofluids can be employed to enhance the efficiency of heat transfer in thermal management and energy systems, such as solar collectors, heat exchangers, and electronic refrigeration, where the current study has real-world applications. Chemical reactors and metallurgical processes are also pertinent, as they are influenced by thermal radiations and MHD control in terms of heat and mass transfer. In addition, these models govern the flow of magnetically controlled nanofluids and reactive transport in biomedical applications and material processing.</p>