<p>Loop heat pipes are two-phase heat transfer devices whose operating principle is based on the evaporation–condensation of a working fluid. In the loop heat pipe, thermal resistance and maximum heat transfer capability are one of the major parameters that are affected by the choice of a working fluid, evaporator and condensation chamber design, the porous wick geometry and thermal properties. Different authors conducted investigations to enhance the heat pipe performance by considering different working fluids and wick materials. To enhance the performance of heat pipe, in present investigation, a loop heat pipe is fabricated with methanol as working fluid and ceramic and stainless steel mesh wire as wick materials. Experiments are conducted to study its performance. After investigations, thermal resistance of ceramic wick is found 20% less than that of stainless steel mesh wire wick. Whereas, thermal conductivity, evaporator heat transfer coefficient, overall heat transfer coefficient and mass flow rate of ceramic wick are 56, 90, 20 and 43% higher than that of stainless steel mesh wire wick. Results conclude that ceramic material shows better performance than stainless steel mesh wire as a wick material.</p>