<p>The general objective of the current study is to carry out a mathematical investigation of transport of solute particle between micro-nano meter scales in blood containing media influenced by the electroosmotic and thermal forces. This research is performed inside a heterogeneous flow conduit filled with a tangent hyperbolic fluid. The interest is more oriented to assessing the behavior of solute nanoparticles and particles confined in a model of the throat and their prospective use in drug provision and biomedical applications using Newtonian fluids and, more specifically, electrically active non-Newtonian electroosmotic fluids. First, this exploration has important consequences for microscale biological processes. Blood is employed as the base fluid, while nanofluids are formed by incorporating Cobalt and Nickel nanoparticles to blood. Each of these nanoparticles is widely used in medical practices where drug delivery and the need to treat cancer come into play. To extend nanomedicine delivery technique, Cobalt and Nickel nanoparticles are also infused into bloodstream together with other minor solute molecules. The mathematical demonstrating is done using rectangular coordinates as flow equalities governing are approximated with linearity with the use of large wavelengths and low Reynolds numbers. The numerical outcomes are calculated for a system of nonlinear equalities that define the dependence of the fluid and particle velocities, temperature, and concentration of the fluid and particles. This work analyzes the effects of different important parameters and shows these effects by the help of graphs. In this work, it is pragmatic that an upsurge in concentration of suspended particle and tangent hyperbolic fluid parameter increases velocity of fluid but temperature distribution declines. The process of introducing particles into the flow slows it down and promotes a temperature rise in the flow when nanoparticles are present.</p>