The production cross-sections of medically relevant radioisotopes, such as \(^{68}\) Ge, \(^{69}\) Ge, \(^{66}\) Ga, \(^{67}\) Ga, and \(^{71}\) As were measured for enriched germanium-70 targets irradiated with an incident 60 MeV proton beam, degraded in the stacked-foil assembly to cover effective energies up to 53 MeV. The targets, with an enrichment level of 95.56%, also contained a 4.36% fraction of \(^{72}\) Ge, necessitating consideration of its contribution of certain reaction products, especially \(^{71}\) As via \(^{72}\) Ge(p,2n) \(^{71}\) As. Irradiation experiments were performed at the AIC-144 cyclotron, followed by \(\gamma\) -ray spectroscopy using high-purity germanium (HPGe) detectors. The excitation functions were compared with TALYS 2.0 nuclear model calculations. Our findings contribute to a more accurate understanding of production routes for diagnostic radioisotopes, highlighting discrepancies with theoretical models and emphasizing the need to account for target isotopic compositions.