<p>The production cross-sections of medically relevant radioisotopes, such as <InlineEquation ID="IEq1"> <EquationSource Format="TEX">\(^{68}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>68</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ge, <InlineEquation ID="IEq2"> <EquationSource Format="TEX">\(^{69}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>69</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ge, <InlineEquation ID="IEq3"> <EquationSource Format="TEX">\(^{66}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>66</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ga, <InlineEquation ID="IEq4"> <EquationSource Format="TEX">\(^{67}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>67</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ga, and <InlineEquation ID="IEq5"> <EquationSource Format="TEX">\(^{71}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>71</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>As were measured for enriched germanium-70 targets irradiated with an incident 60&#xa0;MeV proton beam, degraded in the stacked-foil assembly to cover effective energies up to 53&#xa0;MeV. The targets, with an enrichment level of 95.56%, also contained a 4.36% fraction of <InlineEquation ID="IEq6"> <EquationSource Format="TEX">\(^{72}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>72</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ge, necessitating consideration of its contribution of certain reaction products, especially <InlineEquation ID="IEq7"> <EquationSource Format="TEX">\(^{71}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>71</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>As via <InlineEquation ID="IEq8"> <EquationSource Format="TEX">\(^{72}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>72</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>Ge(p,2n)<InlineEquation ID="IEq9"> <EquationSource Format="TEX">\(^{71}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mn>71</mn> </mmultiscripts> </math></EquationSource> </InlineEquation>As. Irradiation experiments were performed at the AIC-144 cyclotron, followed by <InlineEquation ID="IEq10"> <EquationSource Format="TEX">\(\gamma\)</EquationSource> <EquationSource Format="MATHML"><math> <mi>γ</mi> </math></EquationSource> </InlineEquation>-ray spectroscopy using high-purity germanium (HPGe) detectors. The excitation functions were compared with TALYS 2.0 nuclear model calculations. Our findings contribute to a more accurate understanding of production routes for diagnostic radioisotopes, highlighting discrepancies with theoretical models and emphasizing the need to account for target isotopic compositions.</p>

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Experimental excitation functions of proton-induced reactions on enriched Ge for the production of medical radionuclides

  • Arshiya Anees Ahmed,
  • Ryszard Misiak,
  • Jerzy W. Mietelski,
  • Kamil Brudecki

摘要

The production cross-sections of medically relevant radioisotopes, such as \(^{68}\) 68 Ge, \(^{69}\) 69 Ge, \(^{66}\) 66 Ga, \(^{67}\) 67 Ga, and \(^{71}\) 71 As were measured for enriched germanium-70 targets irradiated with an incident 60 MeV proton beam, degraded in the stacked-foil assembly to cover effective energies up to 53 MeV. The targets, with an enrichment level of 95.56%, also contained a 4.36% fraction of \(^{72}\) 72 Ge, necessitating consideration of its contribution of certain reaction products, especially \(^{71}\) 71 As via \(^{72}\) 72 Ge(p,2n) \(^{71}\) 71 As. Irradiation experiments were performed at the AIC-144 cyclotron, followed by \(\gamma\) γ -ray spectroscopy using high-purity germanium (HPGe) detectors. The excitation functions were compared with TALYS 2.0 nuclear model calculations. Our findings contribute to a more accurate understanding of production routes for diagnostic radioisotopes, highlighting discrepancies with theoretical models and emphasizing the need to account for target isotopic compositions.