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<p>Besides worldwide medical applications of the Positron Emission Tomography assisted by Computed Tomography–PET/CT, this study encompasses the acquisition and reconstruction protocols for imaging of small tropical plants, aiming at the CT optimization and the first feasibility demonstration of 2-deoxy-2-[<sup>18</sup>F]fluoro-D-glucose ([<sup>18</sup>F]FDG) imaging in <i>Peperomia pellucida</i> using a micro-PET/CT system. First, CT protocol optimization was performed using QRM phantom, followed by anatomical and molecular imaging of <i>P. pellucida</i>. The [<sup>18</sup>F]FDG allocation pattern was qualitatively demonstrated in the micro-PET/CT images from the petiole to the stem and possible toward the roots, probably organs of preferential allocation of glucose. The defined preclinical micro-PET/CT system protocol will improve further structural and functional studies in tropical plants.</p>

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Micro-CT phantom-based optimization and [18F]FDG feasibility for molecular imaging of small herbaceous plants using a preclinical PET/CT system

  • 期刊论文

  • 发表日期：

    2026年1月12日

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  • Matheus Andrade Rocha Costa,
  • Brígida Gomes de Almeida Schirmer,
  • Olívia Maria Gomes de Oliveira,
  • Wellen Aguiar de Araújo,
  • Neura Mendes da Silva,
  • Luciana Maria Herculano da Silva,
  • Elvis Joacir De França

摘要

Besides worldwide medical applications of the Positron Emission Tomography assisted by Computed Tomography–PET/CT, this study encompasses the acquisition and reconstruction protocols for imaging of small tropical plants, aiming at the CT optimization and the first feasibility demonstration of 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) imaging in Peperomia pellucida using a micro-PET/CT system. First, CT protocol optimization was performed using QRM phantom, followed by anatomical and molecular imaging of P. pellucida. The [18F]FDG allocation pattern was qualitatively demonstrated in the micro-PET/CT images from the petiole to the stem and possible toward the roots, probably organs of preferential allocation of glucose. The defined preclinical micro-PET/CT system protocol will improve further structural and functional studies in tropical plants.