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<p>This study investigates alanine, glycine, and glutamine as high-dose gamma radiation dosimeters using diffuse reflectance spectroscopy (DRS). DRS provides a non-invasive, cost-effective method for rapid dose estimation. Amino acid powders were irradiated from 0.1 to 100&#xa0;kGy, and their reflectance spectra in the range of 300 to 510&#xa0;nm, were analysed. Non-linear dose–response curves were observed, with alanine, glycine, and glutamine showing peak sensitivities at different dose ranges. Measurements were within ± 6.3% suggesting good reproducibility, stability over time and temperature, and unaffected by dose fractionation. These results highlight amino acids' potential for reliable, long-term radiation dosimetry in routine monitoring applications.</p>

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Dosimetry studies on amino acids using diffuse reflectance measurements for high doses

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月2日

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  • Sandip Mondal,
  • S. H. Shinde,
  • Sneha Chandrasekhar,
  • Probal Chaudhury

摘要

This study investigates alanine, glycine, and glutamine as high-dose gamma radiation dosimeters using diffuse reflectance spectroscopy (DRS). DRS provides a non-invasive, cost-effective method for rapid dose estimation. Amino acid powders were irradiated from 0.1 to 100 kGy, and their reflectance spectra in the range of 300 to 510 nm, were analysed. Non-linear dose–response curves were observed, with alanine, glycine, and glutamine showing peak sensitivities at different dose ranges. Measurements were within ± 6.3% suggesting good reproducibility, stability over time and temperature, and unaffected by dose fractionation. These results highlight amino acids' potential for reliable, long-term radiation dosimetry in routine monitoring applications.