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<p>This study evaluates the feasibility of amorphous silicon (aSi 1000) electronic portal imaging device (EPID) detectors for in vivo dose verification during volumetric modulated arc therapy (VMAT) treatment in prostate cancer. EPID calibration unit (CU) signals were converted into dose using a self-developed algorithm and validated with phantom and patient data. Among 53 patients, mean dose deviation from TPS was &lt; 1%, with 64% within 5% and 7% exceeding 10%. The method demonstrated ~ 5% uncertainty. EPID-based dosimetry offers a practical real-time verification tool, enhancing treatment accuracy and patient safety in clinical radiotherapy.</p>

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Semiconductor based aSi 1000 EPID detectors for in vivo dosimetry for VMAT treatment in prostate cancer: a novel approach to dose verification

  • 期刊论文

  • 发表日期：

    2025年9月13日

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  • Dinesh Kumar,
  • Anirudh Pradhan,
  • Vishnu Chauhan

摘要

This study evaluates the feasibility of amorphous silicon (aSi 1000) electronic portal imaging device (EPID) detectors for in vivo dose verification during volumetric modulated arc therapy (VMAT) treatment in prostate cancer. EPID calibration unit (CU) signals were converted into dose using a self-developed algorithm and validated with phantom and patient data. Among 53 patients, mean dose deviation from TPS was < 1%, with 64% within 5% and 7% exceeding 10%. The method demonstrated ~ 5% uncertainty. EPID-based dosimetry offers a practical real-time verification tool, enhancing treatment accuracy and patient safety in clinical radiotherapy.