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<p>The advent of multifunctional nanoparticles has significantly transformed the landscape of image-guided drug delivery (IGDD) in nuclear medicine. This review presents a detailed examination of the progress and applications of these nanoparticles within the field. It discusses combining imaging techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) with targeted drug delivery platforms, highlighting the nanoparticles’ ability to improve drug bioavailability and therapeutic outcomes. Additionally, the review addresses the challenges related to their translation into clinical practice. By analyzing recent studies and advancements, it seeks to provide insights into the potential of multifunctional nanoparticles for enhancing IGDD in nuclear medicine.</p> Graphical abstract <p></p>

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Multifunctional nanoparticles for image-guided drug delivery in nuclear medicine: advancements and applications

  • 期刊论文

  • 发表日期：

    2025年1月6日

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  • Bilal AbdulMajeed Mukhlif,
  • Muhammad Ikram Ullah,
  • Subasini Uthirapathy,
  • Soumya V. Menon,
  • R. S. K. Sharma,
  • Abed J. Kadhim,
  • Swati Sharma,
  • Bhanu Juneja,
  • Munthar Kadhim Abosaoda,
  • Wesam R. Kadhum

摘要

The advent of multifunctional nanoparticles has significantly transformed the landscape of image-guided drug delivery (IGDD) in nuclear medicine. This review presents a detailed examination of the progress and applications of these nanoparticles within the field. It discusses combining imaging techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) with targeted drug delivery platforms, highlighting the nanoparticles’ ability to improve drug bioavailability and therapeutic outcomes. Additionally, the review addresses the challenges related to their translation into clinical practice. By analyzing recent studies and advancements, it seeks to provide insights into the potential of multifunctional nanoparticles for enhancing IGDD in nuclear medicine.

Graphical abstract