Advancements in radiobiology techniques and applications for personalized radiation therapy in nuclear medicine
摘要
Personalized radiation therapy in Nuclear Medicine aims to tailor treatment regimens to individual patients based on their unique biological characteristics. Recent advancements in radiobiology techniques offer promising avenues for achieving this goal. This review explores key developments in radiobiology, including molecular imaging, radiomics, biomarkers of radiosensitivity, microdosimetry, theranostics, and artificial intelligence. These techniques enable a more precise understanding of tumor biology, prediction of treatment response, and optimization of radiation dose delivery. By integrating radiobiological information into clinical decision-making, personalized radiation therapy in Nuclear Medicine can lead to improved treatment outcomes and reduced side effects.
Graphical abstract