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A DNAzyme-assisted near-infrared upconversion fluorescence sensing strategy for ultra-sensitive, and rapid quantification of uranyl

  • Mi Gong,
  • Xiayu Zhou,
  • Xinxu Yang,
  • Craig A. Grimes,
  • Ziwei Tang,
  • Shengyuan Yang,
  • Yue Wang,
  • Lihao Xiong,
  • Jiayi Song,
  • Le Li,
  • Deshuai Zhen

摘要

Presented is an infrared-induced sensor constructed of upconversion nanoparticles and DNAzyme for ultra-sensitive, and rapid detection of uranyl ions. The detection method eliminates the use of chemically labeled nucleic acid probes, possesses high selectivity, and a uranyl detection limit of 39 nM. The technique is successfully applied to the detection of uranyl in various water samples as well as human serum, illustrating the excellent sensitivity and specificity of the quantification platform.