Synthesis and study of AB₂-type miktoarm star-shaped nanomaterials having glycine as an arm

Coupling-onto approach was equipped to synthesis seven AB₂-type miktoarm stars nanomaterials using carbodiimide chemistry. Glycine, the simplest amino acid is chosen as “arm A”, seven biodegradable amides and polyamides as various “arm B” and amino adipic acid as “core” were used. The structures of these hydrophobic tridentate nano-stars were confirmed with FT-IR and ¹H NMR. The diameter of the nano-stars recorded via DLS ranged from 256.3 nm to 933.4 nm. TGA analysis of the product reported a noticeable loss of 32% by total mass at 400 °C, indicating thermal degradation. The products show significant structural degradation after 15 days of biological treatment with E. coli. All the seven tridentate nano-stars can potentially be equipped as drug-delivery vehicles.