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Fabrication of multi-walled carbon nanotube/polycaprolactone scaffolds for possible application in tissue engineering

  • Jose Peñaranda-Armbrecht,
  • Mario Jose Correa-Quiceno,
  • Julio Cesar Caicedo-Angulo,
  • Paola Andrea Neuta-Arciniegas,
  • José Óscar Gutiérrez-Montes

摘要

Flexible scaffolds made of polycaprolactone (PCL), and multi-walled carbon nanotubes (MWCNTs) were created and chemically verified through RAMAN. The most suitable coupling percentages for PCL were 1%, 3%, and 5% MWCNT. The scaffolds were very stable with high hardness values (10–12 GPa). The PCL/MWCNT 5% scaffold was the most flexible and least resistant, with adequate porosity, pore size, and interconnectivity for cell anchoring. Moreover, the scaffold exhibited low cytotoxicity with a cell viability of 90%. These flexible PCL/MWCNT scaffolds were developed to support tissue engineering by providing a mechanical response with flexibility and elasticity like the surrounding tissue.