<p>This work examined the impact of sodium dodecyl sulfate (SDS) surfactant on the oxidation kinetics of D-glucose employing imidazolium fluorochromate (IFC) as the oxidant. The experiments were conducted under pseudo-first-order conditions at 30&#xa0;°C, with D-glucose in a significantly higher concentration than IFC. The solvent medium used was 50% (v/v) aqueous acetic acid. The reaction demonstrated a first-order dependence on [IFC] and [HClO₄]. The order for [D-glucose] oxidation kinetics was slightly less than one. Perchloric acid acted as a catalyst in this process. The addition of acrylonitrile had no effect on rate constants (<i>k</i>_obs). <i>k</i>_obs decreased with an increase in the concentration of Mn(II) ions. An increase in the dielectric constant of the medium had an inverse effect on <i>k</i>_obs. The initial increase in [SDS] led to a corresponding rise in <i>k</i>_obs, though a saturation in <i>k</i>_obs was observed for elevated [SDS]. The Menger-Portnoy and Piszkiewicz models were used to quantitatively assess the experimental results. The binding constant (<i>K</i>_p), cooperativity index (<i>n</i>), and various thermodynamic parameters in the presence of SDS were calculated. Infrared and mass spectroscopy were used to ascertain D-gluconolactone as the primary product of the reaction. Based on these findings, a reaction scheme has been suggested.</p>