Purpose <p>Intersectoral collaboration is increasingly recognized as a key strategy to address complex work and health challenges, including employment retention among vulnerable populations. This scoping review aims to examine how intersectoral partnerships that support employment retention are conceptualized and studied in the scientific literature and to identify key knowledge gaps.</p> Methods <p>A scoping review was conducted following the Joanna Briggs Institute and Mazaniello-Chézol and Corbière methodologies and was reported in accordance with PRISMA-ScR guidelines. A comprehensive search strategy was developed and applied across multiple databases. Given the absence of literature specifically targeting informal caregivers, the scope was broadened to include workers who face challenges maintaining their participation in the labour market. Data were extracted and analyzed using a framework informed by Bryson’s intersectoral collaboration model.</p> Results <p>The review highlights substantial variability in how intersectoral collaboration is defined and operationalized. Most studies emphasize collaboration among healthcare, employment, and community sectors, focusing on coordination mechanisms, shared goals and resource integration. However, limited attention is given to power dynamics, governance structures, and long-term sustainability. Evidence regarding outcomes remains fragmented, with few studies assessing impacts on job retention or worker health.</p> Conclusion <p>This review provides a structured overview of intersectoral collaboration supporting job retention across diverse populations. It identifies important gaps in conceptual clarity and outcome evaluation. These findings lay a foundation for advancing research and practice related to job retention, including for informal caregivers.</p>