<p>This study shows the creation of an intelligent orthopedic device for arthrodesis using a 4D-printing method. This device has great potential for use in veterinary medicine. The key purpose of such a product for veterinary medicine is to position the joint at a natural angle for the animal, which in modern practice is performed manually by the surgeon. Polylactide (PLA) is selected as the polymer matrix of the composite materials as a biodegradable and bioresorbable polymer obtained from renewable resources that meets the goals of sustainable development by reducing the environmental impact of medical implant production. The effect of secondary temperature treatment and 3D-printing features PLA on the implementation of the shape memory effect (SME) was studied. For a better understanding two well-known dispersed fillers – nanoparticles of hydroxyapatite (HA) and microparticles of silicon dioxide (SiO₂) were chosen. Analyzing the effects of multiple thermal cycling (extrusion followed by 3D-printing), we demonstrate how 4D-printing conditions alter the microstructure, crystallinity, and shape-recovery ability of these materials. The importance of choosing a filler for these technologies is shown, since HA nanoparticles improve interlayer adhesion, while SiO₂ causes cavitation defects. Consequently, 4D-printed PLA/HA showed a high degree of shape recovery (~ 85% recovery coefficient and ~ 3.2&#xa0;MPa recovery stress) and was used to manufacture orthopedic structures. The attachment and activation of self-positioning of the arthrodesis are demonstrated for the accuracy of limb angles and shortening the recovery time of the animal.</p> Graphical Abstract <p></p>