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<p>Normative ranges for vital signs under general anesthesia are well established for healthy pediatric patients, but the influence of The American Society of Anesthesiologists Physical Status (ASA-PS) classification on these normative ranges remains unexplored.&#xa0;The purpose of this study is to develop age-based normative ranges for heart rate (HR) and blood pressure (BP) in patients undergoing general anesthesia for noncardiac surgery in our institution and assess differences by ASA-PS classification.&#xa0;This is a retrospective observational single-center study. We reviewed all anesthetic records from the Hospital for Sick Children, Canada between March 1st and December 31st, 2023. We extracted physiological data from our in-house high-resolution physiological data repository (AtriumDB) to develop normative ranges for physiological parameters and compared them according to ASA-PS classification.&#xa0;We developed age-based normative ranges for BP and HR. We found significant differences between ASA-PS groups, most notably between ASA-PS 1 and 5. We found a statistically significant difference between ASA-PS 1–2 and 3–5 across all physiological parameters.&#xa0;This study validates existing pediatric anesthesia reference ranges while demonstrating the feasibility of incorporating patients across the spectrum of ASA-PS. Further multicenter studies are needed to generalize these findings.</p>

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Development of Normative Ranges for Vital Signs and Differentiation by American Society of Anesthesiologists Physical Status Category: A Retrospective Observational Study

  • 期刊论文

  • 发表日期：

    2025年10月7日

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  • Bruno Caracci,
  • Will Dixon,
  • Rilong Zhang,
  • German Serrano,
  • Spencer Vecile,
  • Andrew Goodwin,
  • Robert Greer,
  • Clyde Matava,
  • Alex Mariakakis,
  • Asad Siddiqui

摘要

Normative ranges for vital signs under general anesthesia are well established for healthy pediatric patients, but the influence of The American Society of Anesthesiologists Physical Status (ASA-PS) classification on these normative ranges remains unexplored. The purpose of this study is to develop age-based normative ranges for heart rate (HR) and blood pressure (BP) in patients undergoing general anesthesia for noncardiac surgery in our institution and assess differences by ASA-PS classification. This is a retrospective observational single-center study. We reviewed all anesthetic records from the Hospital for Sick Children, Canada between March 1st and December 31st, 2023. We extracted physiological data from our in-house high-resolution physiological data repository (AtriumDB) to develop normative ranges for physiological parameters and compared them according to ASA-PS classification. We developed age-based normative ranges for BP and HR. We found significant differences between ASA-PS groups, most notably between ASA-PS 1 and 5. We found a statistically significant difference between ASA-PS 1–2 and 3–5 across all physiological parameters. This study validates existing pediatric anesthesia reference ranges while demonstrating the feasibility of incorporating patients across the spectrum of ASA-PS. Further multicenter studies are needed to generalize these findings.