Acculturative stress is the stress experienced by immigrants and U.S. born populations of Hispanic/Latinos when adapting to a new culture that results from racism, xenophobia, and dissonance between the origin and receiving cultures [7]. The valid and reliable assessment of acculturation stress is a key to helping clinicians and researchers gain a better understanding of stress exposure and potentially aiding in the development of prevention, intervention, and policies to improve overall health and mental health of Hispanic/Latino/as. The aim of this study was to produce a measure that is capable of assessing acculturation stress in both research and clinical settings that can assist in tailoring interventions for this population. The HSI2 original version represents a valid and reliable approach to assessment, yet some settings require a shorter and more expedient tool for acculturation stress assessment. For this reason, the present study aimed to replicate the structure and scope of the HSI2 Immigrant Version in a shorter and abbreviated format (The Abbreviated Immigrant Version of the HSI2). This analysis of an independent sample of Hispanic/Latino immigrants further supported the original conceptualization of acculturation stress as an important psychological construct for researchers and providers who work with and study this growing population group.