<p>Mercury contamination poses a significant environmental and health hazard due to its high toxicity and bioaccumulative nature. The development of highly selective and sensitive sensors for Hg<sup>2+</sup> ion detection has gained immense research interest. Among various chemosensors, imidazole-based fluorescent sensors have emerged as promising moiety due to their unique electronic properties, strong metal-binding affinity, and tunable fluorescence response. This review comprehensively explores the recent advancements in imidazole-functionalized fluorescent probes for Hg<sup>2</sup>⁺ sensing, highlighting different design strategies, sensing mechanisms, and structure–property relationships. This review comprehensively summarizes recent progress in the design and development of imidazole-based fluorescent probes for Hg<sup>2</sup>⁺ detection. Various sensing mechanisms including fluorescence quenching (OFF), fluorescence enhancement (ON), and ratiometric approaches are discussed in relation to their molecular design and structure–property correlations. The analytical performance of these probes is evaluated in terms of sensitivity, selectivity, response time, and applicability in complex sample matrices.</p> Graphical Abstract <p></p>

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Imidazole Derivatives as ON/OFF Fluorescent Chemosensor to Detect Mercury Ion: A Mini Review

  • Suhail Ahmad,
  • Shaik Rabbani,
  • Umme Salma,
  • Salman A. Khan

摘要

Mercury contamination poses a significant environmental and health hazard due to its high toxicity and bioaccumulative nature. The development of highly selective and sensitive sensors for Hg2+ ion detection has gained immense research interest. Among various chemosensors, imidazole-based fluorescent sensors have emerged as promising moiety due to their unique electronic properties, strong metal-binding affinity, and tunable fluorescence response. This review comprehensively explores the recent advancements in imidazole-functionalized fluorescent probes for Hg2⁺ sensing, highlighting different design strategies, sensing mechanisms, and structure–property relationships. This review comprehensively summarizes recent progress in the design and development of imidazole-based fluorescent probes for Hg2⁺ detection. Various sensing mechanisms including fluorescence quenching (OFF), fluorescence enhancement (ON), and ratiometric approaches are discussed in relation to their molecular design and structure–property correlations. The analytical performance of these probes is evaluated in terms of sensitivity, selectivity, response time, and applicability in complex sample matrices.

Graphical Abstract