Scholarlink

<p>Serotonin, a neurotransmitter and also a biomarker for Alzheimer’s as well as Carcinoid Syndrome. It has two important roles in the human body – central as well as peripheral. In the central nervous system, it acts as a neurotransmitter and controls all the brain functions and as a peripheral hormone, it controls the functions of several organs in the body. Herein, we developed a Europium dipicolinic acid (EuDPA) based lanthanide luminescent complex with bright red fluorescence. This fluorescence is further used for the detection of Serotonin (ST). On adding ST, the fluorescence of the probe is quenched. Also, the developed probe shows good selectivity towards other neurotransmitters &amp; co-existing biomolecules. A LoD of 0.99 nM is achieved with this probe. Sensing based on paper-strip was done to check the practicability of the probe, and a real sample analysis was also conducted from spiked human serum/urine samples.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Red Emitting Fluorescent EuDPA Complex as a Probe for the Detection of Serotonin, A Neurotransmitter

  • 期刊论文

  • 发表日期：

    2025年6月18日

查看全文
  • N. S. Vijila,
  • Merin K. Abraham,
  • Greeshma Rajeevan,
  • Geneva Indongo,
  • Arathy B. Kala,
  • Sony George

摘要

Serotonin, a neurotransmitter and also a biomarker for Alzheimer’s as well as Carcinoid Syndrome. It has two important roles in the human body – central as well as peripheral. In the central nervous system, it acts as a neurotransmitter and controls all the brain functions and as a peripheral hormone, it controls the functions of several organs in the body. Herein, we developed a Europium dipicolinic acid (EuDPA) based lanthanide luminescent complex with bright red fluorescence. This fluorescence is further used for the detection of Serotonin (ST). On adding ST, the fluorescence of the probe is quenched. Also, the developed probe shows good selectivity towards other neurotransmitters & co-existing biomolecules. A LoD of 0.99 nM is achieved with this probe. Sensing based on paper-strip was done to check the practicability of the probe, and a real sample analysis was also conducted from spiked human serum/urine samples.