Scholarlink

<p>In recent years, environmentally friendly methods for synthesizing nanoparticles have gained significant attention. This study aimed to develop a green, cost-effective, and facile method for synthesizing ZnO NPs using black chokeberry fruit (<i>Aronia melanocarpa</i> L.<i>)</i> extract and to evaluate their antibacterial, antidiabetic, and photocatalytic activities. Characterization of the phyto-mediated synthesized ZnO NPs was carried out using UV-Visible spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM-EDX) and X-ray diffraction (XRD) analysis. The antioxidant activity of the ZnO NPs was assessed using the 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) radical scavenging assay, yielding a calculated IC<sub>50</sub> value of 154.2&#xa0;µg/mL. The ZnO NPs exhibited effective antibacterial activity against <i>Staphylococcus aureus</i>,<i> Listeria monocytogenes</i>,<i> Salmonella enteritidis</i>, and <i>Escherichia coli</i> with minimum inhibitory concentrations (MIC) of 137.5&#xa0;µg/mL, 135.4&#xa0;µg/mL, 137.7&#xa0;µg/mL, and 185.2&#xa0;µg/mL, respectively. Additionally, the ZnO NPs demonstrated antidiabetic activity by effectively inhibiting α-amylase, an enzyme involved in carbohydrate digestion, with an IC<sub>50</sub> value of 2.355&#xa0;mg/mL. Moreover, the ZnO NPs exhibited significant degradation of methylene blue (MB) dye, achieving a 95.5% degradation efficiency within 120&#xa0;min under UV irradiation. These results suggest that phytogenically synthesized ZnO NPs using black chokeberry fruit extract have great promise for degrading environmental pollutants and may be valuable in various biomedical applications, including antioxidant, antibacterial, and antidiabetic therapies.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Phyto-Mediated Synthesis of Zinc Oxide Nanoparticles Using Black Chokeberry Fruit (Aronia melanocarpa L.) Extracts for Promising Antioxidant, Antibacterial, Antidiabetic, and Photocatalytic Activities

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月2日

查看全文
  • Soner Donmez

摘要

In recent years, environmentally friendly methods for synthesizing nanoparticles have gained significant attention. This study aimed to develop a green, cost-effective, and facile method for synthesizing ZnO NPs using black chokeberry fruit (Aronia melanocarpa L.) extract and to evaluate their antibacterial, antidiabetic, and photocatalytic activities. Characterization of the phyto-mediated synthesized ZnO NPs was carried out using UV-Visible spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM-EDX) and X-ray diffraction (XRD) analysis. The antioxidant activity of the ZnO NPs was assessed using the 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) radical scavenging assay, yielding a calculated IC50 value of 154.2 µg/mL. The ZnO NPs exhibited effective antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella enteritidis, and Escherichia coli with minimum inhibitory concentrations (MIC) of 137.5 µg/mL, 135.4 µg/mL, 137.7 µg/mL, and 185.2 µg/mL, respectively. Additionally, the ZnO NPs demonstrated antidiabetic activity by effectively inhibiting α-amylase, an enzyme involved in carbohydrate digestion, with an IC50 value of 2.355 mg/mL. Moreover, the ZnO NPs exhibited significant degradation of methylene blue (MB) dye, achieving a 95.5% degradation efficiency within 120 min under UV irradiation. These results suggest that phytogenically synthesized ZnO NPs using black chokeberry fruit extract have great promise for degrading environmental pollutants and may be valuable in various biomedical applications, including antioxidant, antibacterial, and antidiabetic therapies.