Scholarlink

<p>Psychomotor retardation (PmR) is a clinically important but understudied feature of depression. Available studies of PmR in depression have also been limited by the reliance on self-report and observation. Instrumental measures, which have been used to assess motor symptoms in neurological disorders, exhibit greater precision and sensitivity than self-report measures and can provide vital information in the clinical presentation. Hence, the present study sought to examine (a) whether depression (diagnosis and/or symptoms) is abnormally associated with an instrumental-based indictaor of PmR, velocity scaling (VS), a behavioral metric that reflects the ability to increase rate of movement across longer versus shorter distances, and (b) the reliability (internal consistency) of VS. A large sample of healthy controls (<i>n</i> = 85) and those with lifetime MDD (<i>n</i> = 146), completed a handwriting task on a tablet. VS was quantified as a slope of change in velocity from 1 to 4&#xa0;cm hand-drawn loops, with steeper slopes indicating less PmR. Whereas VS did not differ between groups, lower VS was significantly negatively related to greater anhedonia across participants, even after covarying for overall depression severity. VS scores also exhibited excellent internal consistency. The handwriting task is a reliable and brief measure that can be completed in only a few minutes and could be a feasible way to assess for PmR in clinical settings. Future studies are needed to determine the temporal relation between VS and anhedonia.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Anhedonia Relates to Increased Psychomotor Retardation Using an Instrumental Handwriting-Based Measure

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月22日

查看全文
  • Riley E. Maher,
  • David M. Klemballa,
  • Sebastian Walther,
  • Vijay A. Mittal,
  • Stewart A. Shankman,
  • Allison M. Letkiewicz

摘要

Psychomotor retardation (PmR) is a clinically important but understudied feature of depression. Available studies of PmR in depression have also been limited by the reliance on self-report and observation. Instrumental measures, which have been used to assess motor symptoms in neurological disorders, exhibit greater precision and sensitivity than self-report measures and can provide vital information in the clinical presentation. Hence, the present study sought to examine (a) whether depression (diagnosis and/or symptoms) is abnormally associated with an instrumental-based indictaor of PmR, velocity scaling (VS), a behavioral metric that reflects the ability to increase rate of movement across longer versus shorter distances, and (b) the reliability (internal consistency) of VS. A large sample of healthy controls (n = 85) and those with lifetime MDD (n = 146), completed a handwriting task on a tablet. VS was quantified as a slope of change in velocity from 1 to 4 cm hand-drawn loops, with steeper slopes indicating less PmR. Whereas VS did not differ between groups, lower VS was significantly negatively related to greater anhedonia across participants, even after covarying for overall depression severity. VS scores also exhibited excellent internal consistency. The handwriting task is a reliable and brief measure that can be completed in only a few minutes and could be a feasible way to assess for PmR in clinical settings. Future studies are needed to determine the temporal relation between VS and anhedonia.