<p>The development of biocompatible and biodegradable information storage devices represents a significant step toward next-generation, eco-friendly electronics. Bio-based resistive-switching memory devices have been successfully fabricated using the gum of <i>Azadirachta indica</i> and <i>Anacardium occidentale</i>, as well as the latex of <i>Artocarpus heterophyllus, Artocarpus altilis,</i> and <i>Calotropis gigantea</i>. The fabricated biomemristor devices, comprising Ag/gum or latex/ITO architecture, exhibited good resistive-switching memory behavior. Remarkably, the gum-based samples demonstrated a moderately high ON/OFF current ratio of 10², whereas the latex-based samples outperformed them with a substantially higher ratio of 10³. This study demonstrates the potential for utilizing gum and latex, often regarded as non-essential byproducts, to fabricate functional devices. The switching mechanism for the memory characteristics can be attributed to the formation of conductive filaments caused by the migration of oxygen vacancies and metal ions through the bioactive layer. Additionally, the resulting devices can degrade naturally without harming the surrounding environment. Therefore, this work is a promising platform for the sustainable development of environmentally friendly or green electronic technologies.</p>