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<p>One important catecholamine neurotransmitter is dopamine, which plays a crucial part in how the human central nervous system works. Neurological disorders and depression are linked to abnormal dopamine release. To realize the physiological roles of dopamine, it is therefore vital to continuously monitor its levels. Cerium dioxide nanorods and zinc oxide nanosheets placed over the prism and silver layers constitute the proposed surface plasmon resonance (SPR) sensor design. Both materials offer unique optical, electrical, and physical properties that improve the SPR sensor’s performance parameters. The transfer matrix method (TMM) and Fresnel equations have been used to examine the performance characteristics. Dopamine (DA) concentration varied, and the sensor’s performance was evaluated. The sensitivity, detection accuracy, and quality factor figures are 72.55&#xa0;deg/RIU, 0.3021&#xa0;deg, and 20.8174 RIU<sup>−1</sup> for single-single Cerium dioxide (CeO<sub>2</sub>) nanorod and zinc oxide (ZnO) nanosheet. As the layers of CeO<sub>2</sub> and ZnO are considered as (C = 1, Z = 15), the highest sensitivity attained is 238.18&#xa0;deg/RIU. The results show that, compared to earlier findings published in the literature up to this point, the proposed SPR-based sensor has a noticeably higher sensitivity. This structure is appropriate for dopamine detection due to its high-performance design parameters.</p>

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Surface plasmon resonance sensor for dopamine detection based on CeO2 nanorod and ZnO nanosheet

  • 期刊论文

  • 发表日期：

    2025年12月22日

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  • Amrindra Pal,
  • Arun Uniyal,
  • Lakshita Phor,
  • Abdullah Saad Alsubaie,
  • Surjeet Chahal,
  • M. Chethan,
  • Helen Merina Albert,
  • Anita Gehlot

摘要

One important catecholamine neurotransmitter is dopamine, which plays a crucial part in how the human central nervous system works. Neurological disorders and depression are linked to abnormal dopamine release. To realize the physiological roles of dopamine, it is therefore vital to continuously monitor its levels. Cerium dioxide nanorods and zinc oxide nanosheets placed over the prism and silver layers constitute the proposed surface plasmon resonance (SPR) sensor design. Both materials offer unique optical, electrical, and physical properties that improve the SPR sensor’s performance parameters. The transfer matrix method (TMM) and Fresnel equations have been used to examine the performance characteristics. Dopamine (DA) concentration varied, and the sensor’s performance was evaluated. The sensitivity, detection accuracy, and quality factor figures are 72.55 deg/RIU, 0.3021 deg, and 20.8174 RIU−1 for single-single Cerium dioxide (CeO2) nanorod and zinc oxide (ZnO) nanosheet. As the layers of CeO2 and ZnO are considered as (C = 1, Z = 15), the highest sensitivity attained is 238.18 deg/RIU. The results show that, compared to earlier findings published in the literature up to this point, the proposed SPR-based sensor has a noticeably higher sensitivity. This structure is appropriate for dopamine detection due to its high-performance design parameters.