<p>This work investigates the application of ferroelectric single crystals of Imidazolium <span>l</span>-Camphorsulfonate (<span>l</span>-ImCS) as Piezoelectric Generators (PEGs) for mechanical energy harvesting. The viability of <span>l</span>-ImCS for this purpose stems from its polar monoclinic P2₁ crystal structure, which is inherently piezoelectric. Dielectric measurements confirmed the ferroelectric nature of the <span>l</span>-ImCS, supporting its functional capabilities. Second Harmonic Generation (SHG) measurements verified the presence of nonlinear optical properties. Intermolecular interactions in the crystal structure were examined using Hirshfeld surface analysis. The Vickers microhardness test assessed the mechanical strength of the grown crystal. The piezoelectric charge coefficient (d₂₂) was calculated as equal to ± 7 pC N⁻¹. UV-visible spectrum measurement indicated excellent transparency in the visible range, indicating its potential for optoelectronic applications. Photoluminescence analysis showed distinct blue and violet emission peaks. The antiviral potential of the synthesized material against pulmonary infections is assessed through molecular docking studies. This research highlights <span>l</span>-ImCS as a promising material for creating eco-friendly power sources capable of driving self-sustaining systems and active sensors.</p>