<p>In this study, CuFe_2-xV_xO₄ ferrite composites were synthesized with different amounts of vanadium oxide (x = 0.00, 0.015, 0.030, and 0.050%). X-ray diffraction and scanning electron microscopy scrutinized the synthesized ceramic’s internal texture. Additionally, a mapping for elemental compositions was performed using EDAX analysis. The X-ray diffraction patterns showed that the insertion of V content changes the phase of the prepared composite from the tetragonal (copper iron oxide) phase to the orthorhombic (Cu₃Fe₄(VO₄)₆) phase. Regarding the γ-ray shielding properties of prepared composites, the Monte Carlo simulation technique was used to evaluate the attenuation parameters for the prepared composites across the energy interval of 0.015–10&#xa0;MeV. The study found that the increase in the V content within the prepared composites decreases their linear attenuation coefficient throughout the ranges of 5.554–4.893&#xa0;cm⁻¹ (at 0.059&#xa0;MeV, 0.354–0.348&#xa0;cm⁻¹ (at 0.662&#xa0;MeV), and 0.136–0.130&#xa0;cm⁻¹ (at 10&#xa0;MeV), respectively, when the V concentration is raised throughout 0–3.6 wt%. This reduction in the linear attenuation coefficient slightly reduces the radiation protection efficiency of the prepared composites when the V doping content increases within the prepared composites.</p>