<p>In this study, we introduce the development and application of a flexible piezoelectric sensor. By incorporating Metal–Organic Framework (UIO-66) and Bi₄Ti₃O₁₂ into P(VDF-HFP), we fabricated a P(VDF-HFP)/MOF/bismuth vacancy Bi₄Ti₃O₁₂ composite nanofiber film and undertook comprehensive characterization and performance evaluations. The findings reveal that the PFP-U0.01BKW composite nanofiber thin film demonstrates superior piezoelectric properties, d₃₃ characteristics, mechanical attributes, and heightened sensitivity. Specifically, the PFP-U0.01BKW exhibits a permittivity of 4.34 at 1&#xa0;kHz, with its elongation at break increasing from 115.1 to 198.8%, while the average Young's modulus drops from 4.4 to 1.3&#xa0;MPa. The d₃₃ value for pure P(VDF-HFP) stands at 4.6 pC/N, whereas the P(VDF-HFP)/MOF/0.01 bismuth vacancy Bi₄Ti₃O₁₂ achieves a d₃₃ value of 14.5. Under forces ranging from 0.098 to 0.98 N, the sensitivity of PFP-U0.01BKW reaches 0.42&#xa0;V/kPa, marking a sevenfold increase compared to pure P(VDF-HFP). The integration of MOF/bismuth vacancy Bi₄Ti₃O₁₂ significantly enhances the film's sensitivity. This paper highlights the potential of the flexible piezoelectric sensor equipped with the PFP-U0.01BKW composite film. It is capable of discerning human body movements by analyzing distinct peaks, frequencies, and shapes, making it suitable for applications in pressure monitoring, motion signal detection, health assessments, and more.</p>