The substantial role of TiO₂ in bimetallic alloy nanoparticle arrangement: electrocatalytic determination of glucose at Ni-Co@TiO₂@GCE

Herein, we investigate glucose detection on Ni-Co supported on TiO₂. The polyol method is used for the synthesis of Ni-Co@TiO₂ nanocomposites (NCs). The morphological and structural properties of Ni-Co@TiO₂ NCs is examined by TEM, SEM, EDX, XRD, while the electrocatalytic properties of Ni-Co@TiO₂@GCE is monitored using voltammetry and amperometry. The Ni-Co@TiO₂@GCE exhibts tremendous electrocatalytic activity towards glucose at a working potential of + 0.45 V. The Ni-Co@TiO₂@GCE shows an excellent response in a wide linear range (0.2–12 mM) with a low limit of detection (0.044 µM), superior sensitivity (2950 µA/mM cm⁻²), stable, and selective response in the presence of interfering species (such as ascorbic acid, uric acid, acetaminophen, NaClz, fructose, xylose, lactose and maltose) within short time o (< 2 s). The Ni-Co@TiO₂@GCE is also applied for determination of glucose in a real blood sample of a diabetic patient.