Ascorbic acid sensing utilizing graphene oxide based on UV–Visible bathochromic shift

This study introduces a novel technique for detecting ascorbic acid (AA) using graphene oxide (GO). As a vital compound in nutrition and healthcare, precise sensing is imperative. Our approach leverages GO's unique properties, capitalizing on its interactions with AA as a reducing agent to establish a robust sensing platform. The UV–Visible spectra of GO revealed distinct absorption peak shifts corresponding to varying AA concentrations. This shift, directly proportional to AA concentration, offers a quantifiable parameter for precise sensing. The observed shift is attributed to AA-induced reduction of GO, restoring π-conjugation within the graphene structure. The US Department of Health and Human Services specifies that the vitamin C amount in our body ranges from 300 mg to 2 ( National Institutes of Health (NIH) Office of Dietary Supplements (ODS) US Department of Health and Human Services, Vitamin C Fact Sheet for Health Professionals, https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/), which falls within the sensing range achieved using UV–Visible spectroscopy. The method prioritizes achieving sensitivity within the specific range, negating the need for excessively high sensitivity. In summary, our innovative GO-based approach provides a suitable method for ascorbic acid sensing with wide-ranging applications in clinical diagnostics, food quality control, and environmental monitoring.