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<p>Pesticides play a vital role in safeguarding crop yields and serve as an important driving force for the progress of modern agriculture. However, the excessive use of pesticides has raised significant concerns regarding their adverse impacts on environments and human health. The development of intelligent stimuli-responsive systems for the controlled release of pesticides represents an effective approach to enhance their efficacy, mitigate environmental contamination, and improve food safety, thereby promoting the sustainable advancement of green agriculture. This review comprehensively discusses recent advancements in pesticide delivery platforms based on metal–organic frameworks (MOFs), with a focus on the classification of MOFs used in nanopesticides and their diverse applications in crop protection, including the management of phytopathogens, pests, weeds, and nutrient deficiencies. The functionality of MOFs further facilitates the development of advanced multi-stimuli-responsive nanopesticide systems, enabling precise and targeted pesticide release. Moreover, this review provides an in-depth discussion on the prospective opportunities and challenges related to the implementation of MOF nanoplatforms in future strategies for sustainable agriculture. Ultimately, we outline a roadmap for translating these laboratory advances into practical applications, emphasizing that the key to successful deployment of MOF-based nanopesticides lies in reconciling agricultural productivity with ecological sustainability.</p> Graphical abstract <p>This review comprehensively discusses recent advancements in pesticide delivery platforms based on metal–organic frameworks (MOFs), with a focus on the classification of MOFs used in nanopesticides and their diverse applications in crop protection, including the management of phytopathogens, pests, weeds, and nutrient deficiencies. Moreover, this review provides an in-depth discussion on the prospective opportunities and challenges related to the implementation of MOF nanoplatforms in future strategies for sustainable agriculture.</p> <p></p>

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Review: metal–organic framework-based controlled-release pesticide formulation for sustainable agriculture

  • 期刊论文

  • 发表日期：

    2026年8月4日

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  • Zetong Yi,
  • Tingting Xiao,
  • Chaonan Jin,
  • Hao Chen,
  • Wei Jin,
  • Zewei Wang,
  • Hongde An

摘要

Pesticides play a vital role in safeguarding crop yields and serve as an important driving force for the progress of modern agriculture. However, the excessive use of pesticides has raised significant concerns regarding their adverse impacts on environments and human health. The development of intelligent stimuli-responsive systems for the controlled release of pesticides represents an effective approach to enhance their efficacy, mitigate environmental contamination, and improve food safety, thereby promoting the sustainable advancement of green agriculture. This review comprehensively discusses recent advancements in pesticide delivery platforms based on metal–organic frameworks (MOFs), with a focus on the classification of MOFs used in nanopesticides and their diverse applications in crop protection, including the management of phytopathogens, pests, weeds, and nutrient deficiencies. The functionality of MOFs further facilitates the development of advanced multi-stimuli-responsive nanopesticide systems, enabling precise and targeted pesticide release. Moreover, this review provides an in-depth discussion on the prospective opportunities and challenges related to the implementation of MOF nanoplatforms in future strategies for sustainable agriculture. Ultimately, we outline a roadmap for translating these laboratory advances into practical applications, emphasizing that the key to successful deployment of MOF-based nanopesticides lies in reconciling agricultural productivity with ecological sustainability.

Graphical abstract

This review comprehensively discusses recent advancements in pesticide delivery platforms based on metal–organic frameworks (MOFs), with a focus on the classification of MOFs used in nanopesticides and their diverse applications in crop protection, including the management of phytopathogens, pests, weeds, and nutrient deficiencies. Moreover, this review provides an in-depth discussion on the prospective opportunities and challenges related to the implementation of MOF nanoplatforms in future strategies for sustainable agriculture.