<p>The slow crack growth (SCG) resistance of polyethylene (PE) is closely related to the chain entanglement characteristics in the amorphous phase. Owing to limitations in direct measurement techniques, detailed information on chain entanglements in solid PE remains inaccessible. This study leverages the preservation of entanglements in the amorphous phase during solidification to characterize SCG resistance via melt-phase entanglement parameters. Through shear rheological analysis, the entanglement densities of five PE resins are determined. Additionally, the concept of the relative number of entanglements (RNE) is proposed, integrating the theoretical amorphous phase volume (TAPV) with entanglement density. The results show that there is a lack of clear correlation between entanglement density and SCG resistance determined by the strain hardening modulus (SHM); in contrast, RNE exhibits a strong correlation with the SCG resistance for PE resins with comparable short chain branch (SCB) contents. To address the limitations of RNE, the normalized natural draw ratio (NNDR) is developed as a supplementary indicator. NNDR is sensitive to the effect of the SCB content on the SCG resistance, but this parameter becomes invalid for PE resins with similar molecular weight distribution (MWD) and short chain branch distribution (SCBD). Finally, a combined RNE-NNDR diagrammatic method is established to extend the applicability of SCG resistance evaluation for PE resins.</p>