Scholarlink

<p>Accurate temperature sensing at the nanoscale is critical for applications in cellular thermometry and micro-electromechanical systems (MEMS), yet it remains challenging due to the low quantum yield and signal attenuation of conventional upconversion nanothermometers. To address this limitation, we developed an innovative platform integrating gold microsphere arrays with core–shell upconversion nanoparticles (NaGdF<sub>4</sub>:Yb,Er@NaYF<sub>4</sub>). This design leverages localized surface plasmon resonance and thermal confinement effects to enhance both optical excitation and thermal response. Experimental results demonstrate a 4200% increase in fluorescence intensity and an 85% improvement in temperature sensitivity compared to isolated nanoparticles. The platform’s ability to simultaneously amplify signal output and thermal response offers a new strategy for high-performance nanothermometry. This work paves the way for precise temperature monitoring in biological systems, such as real-time thermal mapping of living cells under photothermal therapy.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Enhanced temperature sensing sensitivity of upconversion nanoparticles based on thermal localization of gold microsphere arrays

  • 期刊论文

  • 发表日期：

    2026年3月23日

查看全文
  • Chuangxin Wu,
  • Guozheng Nie,
  • Shiping Zhan,
  • Xiaofeng Wu,
  • Yunxin Liu

摘要

Accurate temperature sensing at the nanoscale is critical for applications in cellular thermometry and micro-electromechanical systems (MEMS), yet it remains challenging due to the low quantum yield and signal attenuation of conventional upconversion nanothermometers. To address this limitation, we developed an innovative platform integrating gold microsphere arrays with core–shell upconversion nanoparticles (NaGdF4:Yb,Er@NaYF4). This design leverages localized surface plasmon resonance and thermal confinement effects to enhance both optical excitation and thermal response. Experimental results demonstrate a 4200% increase in fluorescence intensity and an 85% improvement in temperature sensitivity compared to isolated nanoparticles. The platform’s ability to simultaneously amplify signal output and thermal response offers a new strategy for high-performance nanothermometry. This work paves the way for precise temperature monitoring in biological systems, such as real-time thermal mapping of living cells under photothermal therapy.