<p>In this study, we developed a fluorescent sensor based on a pyrene-derived covalent organic framework (PT<sub>2</sub>D-COFs) for the efficient and sensitive detection of copper ions (Cu<sup>2+</sup>) and iron ions (Fe<sup>3+</sup>). The PT<sub>2</sub>D-COFs are synthesized via a Schiff base reaction, exhibiting high crystallinity, excellent porosity, and remarkable chemical stability, which provide ideal coordination sites for the effective recognition of metal ions. The results demonstrate that the PT<sub>2</sub>D-COFs exhibit significant fluorescence quenching upon interaction with Cu<sup>2</sup>⁺, with a detection limit (LOD) of 0.79&#xa0;nM, while fluorescence enhancement is observed in the presence of Fe<sup>3+</sup>, with an LOD of 0.47&#xa0;nM. and reproducibility in complex sample matrices. It was effectively utilized to quantify Cu<sup>2+</sup> and Fe<sup>3+</sup> in environmental water samples and traditional Chinese herbal medicines, achieving satisfactory recovery rates. This sensor demonstrates characterized by its low detection limits, strong anti-interference capability, and broad application potential, holds significant promise for applications in environmental monitoring and bioanalysis.</p> Graphical abstract <p></p>

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A pyrene-based covalent organic framework fluorescence sensor with dual response for highly sensitive detection of Cu2+ and Fe3+

  • Mei You,
  • Zixuan Zhou,
  • Xinying Yan,
  • Haotian Xie,
  • Xueke Chen,
  • Jing Zhang,
  • Fusheng Liao,
  • Guobing Wei,
  • Hao Fan,
  • Zhaojiang Yin

摘要

In this study, we developed a fluorescent sensor based on a pyrene-derived covalent organic framework (PT2D-COFs) for the efficient and sensitive detection of copper ions (Cu2+) and iron ions (Fe3+). The PT2D-COFs are synthesized via a Schiff base reaction, exhibiting high crystallinity, excellent porosity, and remarkable chemical stability, which provide ideal coordination sites for the effective recognition of metal ions. The results demonstrate that the PT2D-COFs exhibit significant fluorescence quenching upon interaction with Cu2⁺, with a detection limit (LOD) of 0.79 nM, while fluorescence enhancement is observed in the presence of Fe3+, with an LOD of 0.47 nM. and reproducibility in complex sample matrices. It was effectively utilized to quantify Cu2+ and Fe3+ in environmental water samples and traditional Chinese herbal medicines, achieving satisfactory recovery rates. This sensor demonstrates characterized by its low detection limits, strong anti-interference capability, and broad application potential, holds significant promise for applications in environmental monitoring and bioanalysis.

Graphical abstract