Scholarlink

<p>In this study, we capitalized on the optical properties of liquid crystal molecules to accomplish the detection of tetracycline (TC). Specifically, the long—chain molecule N,N-Dimethyloctadecyl [3—(trimethoxysilylpropyl)] ammonium chloride (DMOAP) was employed to direct liquid crystal molecules vertically, maintaining their perpendicularity to the substrate surface. The short—chain molecule triethoxybutyraldehyde silane (TEBS) featured an aldehyde group at one terminus, which was exploited to immobilize tetracycline antibodies (anti-TC). Through the specific binding reactions between these antibodies and tetracycline, tetracycline was immobilized onto the substrate surface. Silver nanoparticles (AgNPs) were introduced as signal amplifiers, enabling the detection of tetracycline at low concentrations. By comprehensively investigating the concentration of the analyte and its corresponding grayscale values, we discovered a linear correlation between concentration and grayscale values, which could be described by the equation: <i>y</i> = 0.731X + 1.458. Eventually, we successfully realized the detection of tetracycline, with a detection limit as low as 0.071&#xa0;ng/mL.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Detection of tetracycline by liquid crystal biosensor based on AgNPs signal amplifier

  • 期刊论文

  • 发表日期：

    2025年12月9日

查看全文
  • Jia Xu,
  • Lei Wang,
  • Fei Hong,
  • Xiaojuan Lai,
  • Xin Wen,
  • Wenwen Yang

摘要

In this study, we capitalized on the optical properties of liquid crystal molecules to accomplish the detection of tetracycline (TC). Specifically, the long—chain molecule N,N-Dimethyloctadecyl [3—(trimethoxysilylpropyl)] ammonium chloride (DMOAP) was employed to direct liquid crystal molecules vertically, maintaining their perpendicularity to the substrate surface. The short—chain molecule triethoxybutyraldehyde silane (TEBS) featured an aldehyde group at one terminus, which was exploited to immobilize tetracycline antibodies (anti-TC). Through the specific binding reactions between these antibodies and tetracycline, tetracycline was immobilized onto the substrate surface. Silver nanoparticles (AgNPs) were introduced as signal amplifiers, enabling the detection of tetracycline at low concentrations. By comprehensively investigating the concentration of the analyte and its corresponding grayscale values, we discovered a linear correlation between concentration and grayscale values, which could be described by the equation: y = 0.731X + 1.458. Eventually, we successfully realized the detection of tetracycline, with a detection limit as low as 0.071 ng/mL.

Graphical abstract