<p>In this research review, we emphasize a novel field of study focused on innovative MXene composites in advanced biomedical applications, utilizing their distinct characteristics to enhance cell labeling, thermal therapy, and imaging. MXenes have very high conductivity, are safe for living things, and have surface chemical properties that can be changed. In the field of biomedical nanomaterials, drug delivery, antimicrobial activity, chemotherapeutics, hydrophobicity, biosensors and bioelectronics, regenerative medicine, bioaffinity, and diagnostic imaging like CT and MRI are all things that scientists look at. MXene-based composites are made to improve bioactive heat therapy by making heat transfer better and temperature control more accurate. Also, the special optical properties of these composites make them very useful for advanced cell imaging, which lets you see how cells are working and how they respond to treatment in real time. You can also make the composites so that they label specific cells, which lets you find and follow different groups of cells. This cutting-edge platform makes personalized precision medicine possible and has a big effect on theranostic technologies, which combine treatment and diagnostic tools to help prevent and manage a wide range of diseases.</p> Graphical Abstract <p></p>