<p>The purpose was to evaluate clinical characteristics and outcomes of patients under 18 years of age submitted for an electrophysiological study (EPS) for the presence of a manifest accessory pathway (AP) and to compare conventional versus non‑radiological navigation system (NRNS) technics. An observational, multicenter and analytical study was conducted using Latin American Heart Rhythm Society´s pediatric registry. A total of 746 patients underwent EPS due to manifest AP and were all included. The mean age was 10,5 ± 4,4 years, and 471 (63.1%) were male. There were 68 (9,1%) with a structural heart disease and Ebstein’s anomaly was the most frequent congenital heart disease (CHD). Ablation was attempted in 734 (98.4%) and was successful in 694 (94.6%). A NRNS was used in 218 (28.8%) procedures and radiofrequency was used in 728 (97.6%). There were 22 (2.9%) complications, including complete AV block requiring pacemaker implantation in 2 (0.3%) cases. No deaths were reported. After at least one-year follow-up there were 64 (2.2%) patients with manifest AP recurrence. Patients in NRNS group were older (11,6 ± 3,7 vs., 9,6 ± 4,7 years, <i>p</i> &lt; 0,001), had more CHD (13,5% vs. 6,2%, <i>p</i> = 0,004), required less fluoroscopy (6,9 ± 5,9 vs. 20,2 ± 16,5 min, <i>p</i> &lt; 0,001) and achieved higher acute success (99,1% vs. 92,7%, p &lt; 0,001). There were no differences in complications or recurrences. In the multivariate analysis, only the use of NRNS was independently associated with greater effectiveness (<i>p</i> = 0.019). This study reports clinical characteristics, EPS and ablation in children with manifest AP. Ablation using a NRNS was more effective and required less fluoroscopy, without compromising safety.</p><p>Capsule Summary: In 746 children undergoing EPS for manifest accessory pathways, ablation showed high effectiveness and low complication rates. Non-radiological navigation systems (NRNS) achieved higher acute success and markedly reduced fluoroscopy without compromising safety. Multivariate analysis identified NRNS as an independent predictor of greater effectiveness.</p> Graphical Abstract <p></p>

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Ablation of manifest accessory pathways in pediatric patients: comparison between conventional and non‑radiological navigation techniques

  • Alejandro Cuesta,
  • María J. Arocena,
  • José M. Moltedo,
  • Fernando Vidal,
  • Pedro Iturralde,
  • Manlio Márquez-Murillo,
  • Moisés Levinstein J,
  • Santiago Nava,
  • Gerardo Rodríguez-Diez,
  • Elaine Nuñez,
  • Luis Wayar,
  • Luis J. Colin Lizalde,
  • Jorge R. Gómez Flores,
  • José L. Morales,
  • Rogelio Robledo,
  • Alejandro Estrada,
  • Andrés Caeiro,
  • Katty Quezada,
  • Álvaro Arenas,
  • Michel Cabrera Ortega

摘要

The purpose was to evaluate clinical characteristics and outcomes of patients under 18 years of age submitted for an electrophysiological study (EPS) for the presence of a manifest accessory pathway (AP) and to compare conventional versus non‑radiological navigation system (NRNS) technics. An observational, multicenter and analytical study was conducted using Latin American Heart Rhythm Society´s pediatric registry. A total of 746 patients underwent EPS due to manifest AP and were all included. The mean age was 10,5 ± 4,4 years, and 471 (63.1%) were male. There were 68 (9,1%) with a structural heart disease and Ebstein’s anomaly was the most frequent congenital heart disease (CHD). Ablation was attempted in 734 (98.4%) and was successful in 694 (94.6%). A NRNS was used in 218 (28.8%) procedures and radiofrequency was used in 728 (97.6%). There were 22 (2.9%) complications, including complete AV block requiring pacemaker implantation in 2 (0.3%) cases. No deaths were reported. After at least one-year follow-up there were 64 (2.2%) patients with manifest AP recurrence. Patients in NRNS group were older (11,6 ± 3,7 vs., 9,6 ± 4,7 years, p < 0,001), had more CHD (13,5% vs. 6,2%, p = 0,004), required less fluoroscopy (6,9 ± 5,9 vs. 20,2 ± 16,5 min, p < 0,001) and achieved higher acute success (99,1% vs. 92,7%, p < 0,001). There were no differences in complications or recurrences. In the multivariate analysis, only the use of NRNS was independently associated with greater effectiveness (p = 0.019). This study reports clinical characteristics, EPS and ablation in children with manifest AP. Ablation using a NRNS was more effective and required less fluoroscopy, without compromising safety.

Capsule Summary: In 746 children undergoing EPS for manifest accessory pathways, ablation showed high effectiveness and low complication rates. Non-radiological navigation systems (NRNS) achieved higher acute success and markedly reduced fluoroscopy without compromising safety. Multivariate analysis identified NRNS as an independent predictor of greater effectiveness.

Graphical Abstract