The prevalence, distribution and ablation of non-pulmonary vein triggers in older patients with paroxysmal atrial fibrillation
摘要
To investigate the prevalence, distribution and ablation of non-pulmonary vein (PV) triggers in older patients with paroxysmal atrial fibrillation (AF).
MethodsA total of 694 patients aged 65–80 receiving index ablation for paroxysmal AF were included. These patients were divided as follows: patients without low-voltage areas (LVA) (n = 437), LVA patients with modification (n = 175), and LVA patients without modification (n = 82). Following propensity score matching (PSM) analysis, two sets of matched groups emerged: LVA patients without modification (Group A, n = 77) and patients without LVA (Group B, n = 77), and patients without LVA (Group C, n = 168) and LVA patients with modification (Group D, n = 168). The clinical endpoint was defined as the detection of ATA lasting longer than 30 s through ECG documentation or Holter recordings following the index ablation.
ResultsFifty-seven (8.2%) patients were identified with non-PV triggers, mostly originating from superior vena cava (SVC). Compared with Group A, Group B exhibited a higher prevalence of non-PV triggers (18.2% vs. 6.5%, p = 0.027). Likewise, Group C showed a higher prevalence compared with Group D (14.3% vs 7.1%, p = 0.034). Over a mean follow-up of 19.7 months, there was no significant difference in ATA recurrence between patients with non-PV triggers ablation (n = 57) and without non-PV triggers (n = 637) (71.9% vs 74.9%, p = 0.458).
ConclusionsAmong older patients with paroxysmal AF, non-PV triggers exhibit a lower prevalence, originate mostly from SVC, and present less frequently in patients with LVA.
Graphical Abstract