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<p>This article presents a computational study of the Hodgkin-Huxley model and the simulation of action potential propagation in an unmyelinated axon using the finite volume method. By implementing a voltage-clamp patch and tracking detailed ionic and capacitive currents and channel gating, we achieve robust and unit-consistent simulation of action potential initiation and propagation.</p>

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A charge conservative finite volume discretization of the Hodgkin-Huxley model

  • 期刊论文

  • 发表日期：

    2026年5月12日

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  • Muhammad Zeeshan Ashraf,
  • Tanel Peets,
  • Kert Tamm

摘要

This article presents a computational study of the Hodgkin-Huxley model and the simulation of action potential propagation in an unmyelinated axon using the finite volume method. By implementing a voltage-clamp patch and tracking detailed ionic and capacitive currents and channel gating, we achieve robust and unit-consistent simulation of action potential initiation and propagation.