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An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A)

  • Norbert Gleicher,
  • David H. Barad,
  • Pasquale Patrizio,
  • Sonia Gayete-Lafuente,
  • Andrea Weghofer,
  • Zion Ben Rafael,
  • Shizuko Takahashi,
  • Demián Glujovsky,
  • Ben W. Mol,
  • Raoul Orvieto

摘要

After over 20 years of progressively increasing clinical utilization of PGT-A (and its precursors), the American Society for Reproductive Medicine (ASRM) and its daughter society, the Society for Assisted Reproduction (SART), for the first time published a committee opinion clearly acknowledging that “the value of PGT-A as a routine screening test for patients undergoing in vitro fertilization (IVF) has not been demonstrated.” This statement is timely and welcome but requires some additions and raises some new questions, among those why, if PGT-A in a general population does not improve IVF cycle outcomes, the routine clinical utilization of PGT-A should continue.