<p>A UV visible spectroscopic method has been developed for the simultaneous estimation of quercetin and ellagic acid in a suspension. Validation of the developed method was done according to ICH Q2R2 guidelines. Calibration curves (R<sup>2</sup> &gt; 0.98) were prepared, demonstrating a linear response for the concentration ranges of both drugs. The results indicated high levels of accuracy and precision (all %RSD values &lt;2%). The findings suggest that this method can be readily adopted in routine laboratory settings, facilitating the simultaneous monitoring of drug levels in both bulk and dosage forms.</p>

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UV Spectroscopy-Based Development and Validation of an Analytical Method for Simultaneous Estimation of Ellagic Acid and Quercetin in Bulk Suspension

  • Kabil Malhotra,
  • Kalpana Nagpal

摘要

A UV visible spectroscopic method has been developed for the simultaneous estimation of quercetin and ellagic acid in a suspension. Validation of the developed method was done according to ICH Q2R2 guidelines. Calibration curves (R2 > 0.98) were prepared, demonstrating a linear response for the concentration ranges of both drugs. The results indicated high levels of accuracy and precision (all %RSD values <2%). The findings suggest that this method can be readily adopted in routine laboratory settings, facilitating the simultaneous monitoring of drug levels in both bulk and dosage forms.