Purpose <p>This study aims to comprehensively evaluate the relationships between TMJ dysfunction, cervical posture, functional balance, dual-task performance, and social adaptive skills in individuals with Autism Spectrum Disorder (ASD).</p> Methods <p>The study included 23 individuals with ASD aged 4–17 years and 23 age- and gender-matched typically developing controls. Participant information was collected using a case evaluation form. TMJ dysfunction was assessed using the Helkimo Index, cervical posture using the PostureScreen application, and functional balance using the Timed Up and Go (TUG) test. Dual-task performance was evaluated through motor and cognitive task combinations, and social adaptation was measured with the Vineland Adaptive Behavior Scale.</p> Results <p>the ASD group had significantly longer TUG durations compared to controls (<i>p</i> &lt; 0.05). Mandibular movements and Helkimo Index scores were also significantly higher in the ASD group (<i>p</i> &lt; 0.05). In the Ten-Meter Walk Test across all motor and dual-task conditions, the ASD group again demonstrated significantly longer durations (<i>p</i> &lt; 0.05). No significant differences were found in cervical range of motion between groups (<i>p</i> &gt; 0.05). However, the ASD group scored significantly lower on Vineland total and subscale scores (<i>p</i> &lt; 0.05). Postural analysis revealed significant differences in several head and shoulder displacement distances and angles (<i>p</i> &lt; 0.05). Moderate positive correlations were found between the Ten-Meter Motor Test (and its sub-dimensions) and Helkimo scores.</p> Conclusion <p>Individuals with ASD exhibit TMJ dysfunction, balance impairments, dual-task difficulties, and reduced social adaptation skills, supporting the need for multidimensional assessment approaches.</p>