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Purpose <p>Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and single-gene cause of autism. The Stanford-Binet, Fifth Edition (SB-5) is commonly used to assess IQ in FXS. It is not known if the SB-5 routing form’s abbreviated IQ (ABIQ) score accurately estimates full-scale IQ (FSIQ), limiting data-informed decision-making when choosing between an abbreviated or full SB-5 battery.</p> Methods <p>198 participants with FXS (143 males) aged 4 to 47 years of age completed the full SB-5. We calculated differences between abbreviated and full-scale estimates of IQ and assessed the extent to which the agreement between ABIQ and FSIQ varied as a function of age, routing subtest scatter, and FSIQ.</p> Results <p>The abbreviated SB-5 battery over-estimated FSIQ in most school-age children (&lt; 11 years), and under-estimated FSIQ in adolescents and adults. This under-estimate of FSIQ was larger when there was a greater discrepancy (scatter) between the two routing subtests that comprise ABIQ and in individuals with FSIQ &lt; 68.</p> Conclusion <p>Clinicians and researchers should consider administering the full SB-5 battery to individuals with FXS when possible. If only an abbreviated estimate of IQ is available, ABIQ should be interpreted with caution based on our findings of over- or under-estimation occurring across development. Large discrepancies between verbal and nonverbal skills as well as greater severity of ID should both serve as cues to administer the full battery to avoid under-estimating cognitive skills that are otherwise only captured by FSIQ.</p>

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Brief Report: Differences Between Stanford-Binet Abbreviated and Full-Scale Estimates of IQ in Fragile X Syndrome Vary Across Development

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月23日

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  • Walker S. McKinney,
  • Meredith Nelson,
  • Rebecca C. Shaffer,
  • Kelli C. Dominick,
  • Craig A. Erickson,
  • Lauren M. Schmitt

摘要

Purpose

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and single-gene cause of autism. The Stanford-Binet, Fifth Edition (SB-5) is commonly used to assess IQ in FXS. It is not known if the SB-5 routing form’s abbreviated IQ (ABIQ) score accurately estimates full-scale IQ (FSIQ), limiting data-informed decision-making when choosing between an abbreviated or full SB-5 battery.

Methods

198 participants with FXS (143 males) aged 4 to 47 years of age completed the full SB-5. We calculated differences between abbreviated and full-scale estimates of IQ and assessed the extent to which the agreement between ABIQ and FSIQ varied as a function of age, routing subtest scatter, and FSIQ.

Results

The abbreviated SB-5 battery over-estimated FSIQ in most school-age children (< 11 years), and under-estimated FSIQ in adolescents and adults. This under-estimate of FSIQ was larger when there was a greater discrepancy (scatter) between the two routing subtests that comprise ABIQ and in individuals with FSIQ < 68.

Conclusion

Clinicians and researchers should consider administering the full SB-5 battery to individuals with FXS when possible. If only an abbreviated estimate of IQ is available, ABIQ should be interpreted with caution based on our findings of over- or under-estimation occurring across development. Large discrepancies between verbal and nonverbal skills as well as greater severity of ID should both serve as cues to administer the full battery to avoid under-estimating cognitive skills that are otherwise only captured by FSIQ.