Scholarlink

Purpose <p>The purpose of this study is to identify objective, biological markers —biomarkers— that can signal ASD risk earlier and more reliably.</p> Methods <p>A structured literature search was carried out between 2010 and 2025 in PubMed, Scopus, Web of Science, Google Scholar, and Science Direct.</p> Results <p>Twenty (20) empirical studies were identified, meeting inclusion criteria, encompassing microbial taxa, short-chain fatty acids (SCFAs), fungal species, urinary metabolites, amino acids, and oxidative stress markers.</p> Conclusions <p>This review underscores the promise of non-genetic biomarkers in advancing early, objective, and biologically grounded ASD diagnosis, while emphasizing the need for large-scale, longitudinal studies to validate findings and translate them into clinical practice.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Gut and Metabolic Biomarkers in Autism Spectrum Disorder: A Systematic Review of Body Fluid Signatures for Early Detection

  • 期刊论文

  • 发表日期：

    2025年9月26日

查看全文
  • Christine K. Syriopoulou-Delli,
  • Deeksha Chaudhuri

摘要

Purpose

The purpose of this study is to identify objective, biological markers —biomarkers— that can signal ASD risk earlier and more reliably.

Methods

A structured literature search was carried out between 2010 and 2025 in PubMed, Scopus, Web of Science, Google Scholar, and Science Direct.

Results

Twenty (20) empirical studies were identified, meeting inclusion criteria, encompassing microbial taxa, short-chain fatty acids (SCFAs), fungal species, urinary metabolites, amino acids, and oxidative stress markers.

Conclusions

This review underscores the promise of non-genetic biomarkers in advancing early, objective, and biologically grounded ASD diagnosis, while emphasizing the need for large-scale, longitudinal studies to validate findings and translate them into clinical practice.